<scp>FADD</scp> expression is associated with regional and distant metastasis in squamous cell carcinoma of the head and neck

Abstract

Our data show that an increase in FADD expression is associated with a higher incidence of lymph node metastasis at presentation, and with shorter DMFI when lymph node metastases are present. High FADD expression in the primary tumour could be a useful marker to select patients for systemic treatment strategies that reduce the risk of distant metastases.