Pharmacokinetic Interactions Between the Hepatitis C Virus Protease Inhibitor Boceprevir and Ritonavir-Boosted HIV-1 Protease Inhibitors Atazanavir, Darunavir, and Lopinavir - Concepedia

Concepedia

Publication | Open Access

Pharmacokinetic Interactions Between the Hepatitis C Virus Protease Inhibitor Boceprevir and Ritonavir-Boosted HIV-1 Protease Inhibitors Atazanavir, Darunavir, and Lopinavir

DOI Full Paper Access

77

Citations

19

References

2012

Year

Ellen G. J. Hulskotte, Hwa-ping Feng, Fengjuan Xuan, Marga G. J. A. van Zutven, Michelle Treitel, Eric Hughes, Edward O’Mara, Stephen P. Youngberg, John A. Wagner, Joan R. Butterton

Clinical Infectious Diseases

Abstract

Concomitant administration of boceprevir with PI/r resulted in reduced exposures of PI and boceprevir. These drug-drug interactions may reduce the effectiveness of PI/r and/or boceprevir when coadministered.

References

	Year	Citations

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