2002 · 862 citations · 26 references
Life SciencesBioinformaticsEvolutionary BiologyComputational BiologyGenomicsPhylogeneticsPhylogenetic AnalysisPhylogenetic Tree ReconstructionGene Family AnalysisPopulation-level Variation
Phylogentic analysis is becoming an increasingly important tool for customized drug treatments, epidemiological studies, and evolutionary analysis. The TCS method provides an important tool for dealing with genes at a population level. Existing software for TCS analysis takes an unreasonable amount of time for the analysis of significant numbers of Taxa. This paper presents the TCS algorithms and describes initial attempts at parallelization. Performance results are also presented for the algorithm on several data sets.
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Inferring the historical patterns of biological evolution
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Life Sciences, Biology, Zoology +11
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