A Randomized Trial on the Optimization of ¹⁸F-FDG Myocardial Uptake Suppression: Implications for Vulnerable Coronary Plaque Imaging

Abstract

A high-fat low-carbohydrate meal followed by a 12-h fasting period effectively suppressed myocardial (18)F-FDG uptake in most subjects. Neither complementary fatty acid loading nor verapamil administered 1 h before (18)F-FDG injection conferred any additional benefit. Myocardial (18)F-FDG uptake was inversely correlated with cFFA level, representing an interesting way to predict myocardial (18)F-FDG uptake suppression.