Desmoplastic trichoepithelioma versus morphoeic basal cell carcinoma: a critical reappraisal of histomorphological and immunohistochemical criteria for differentiation

Abstract

Histopathologistics need to identify with confidence subtle signs of infundibular, follicular and sebaceous differentiation because these features are dependable criteria to differentiate DTE from MBCC. Immunohistochemistry for androgen receptors and CK20 is helpful, but interpretation is difficult in some DTEs when few cells are immunopositive for these markers.