POSSIBLE MECHANISMS INDUCING GLOMERULATIONS IN INTERSTITIAL CYSTITIS: RELATIONSHIP BETWEEN ENDOSCOPIC FINDINGS AND EXPRESSION OF ANGIOGENIC GROWTH FACTORS

Abstract

Glomerulations during hydrodistention are highly associated with the over expression of angiogenic growth factors in the bladder. Thus, it seems likely that neovascularization promoted by angiogenic growth factors has an important role in the pathogenesis of IC, inducing glomerulations during hydrodistension.