Antioxidants attenuate myocyte apoptosis in the remote non-infarcted myocardium following large myocardial infarction

Abstract

Long-term treatment with the antioxidants probucol and pyrrolidine dithiocarbamate attenuates oxidative stress, myocyte apoptosis, caspase-3 like activity and the expression of p53, bax and caspase-3 within RM in rats after a large myocardial infarction.