Stereoselective Synthesis of Metalated Cyclobutyl Derivatives

Abstract

Abstract magnified image Treatment of Z ‐vinyl carbamates with dicyclopentadienyl(diethyl)zirconium [Et 2 ZrCp 2 ] leads to cyclobutyl‐zirconocene derivatives in good yields and as a unique diastereoisomer. The reaction proceeds through a carbometalative ring‐expansion followed by an intramolecular migratory insertion.