Genetic interaction of <i>PICALM</i> and <i>APOE</i> is associated with brain atrophy and cognitive impairment in Alzheimer's disease - Concepedia

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Genetic interaction of <i>PICALM</i> and <i>APOE</i> is associated with brain atrophy and cognitive impairment in Alzheimer's disease

56

Citations

27

References

2014

Year

Katrin Morgen, Alfredo Ramı́rez, Lutz Frölich, Heike Tost, Michael M. Plichta, Heike Kölsch, F. Rakebrandt, Otto Rienhoff, Frank Jessen, Oliver Peters,

Alzheimer s & Dementia

Abstract

The data suggest a neural mechanism for APOE-PICALM interactions in patients with manifest AD and indicate that the PICALM genotype modulates both brain atrophy and cognitive performance in APOE ε4 carriers.

References

	Year	Citations

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