An Approach for Balancing Diagnostic Image Quality with Cancer Risk: Application to Pediatric Diagnostic Imaging of ^99mTc-Dimercaptosuccinic Acid

Abstract

The study illustrates implementation of a rigorous approach for balancing the benefits of adequate image quality against the radiation risks and also demonstrates that weight-based adjustment to the administered activity is suboptimal. Extension of this methodology to other radiopharmaceuticals would yield the data required to generate objective and well-founded administered activity guidelines for pediatric and other patients.