Clinical Infectious Diseases · 1998 · 44 citations · 11 references
MedicineInfectious DiseasesMicrobiologyMicrobial PathogenesisNeonatologyPediatric Infectious DiseasesCongenital InfectionsFungal InfectionsFungal PathogenesisNeonatal InfectionsNeonatal Infectious DiseasesSkin InfectionsAntifungal Therapy In NeonatesDisseminated Fungal InfectionFungal Infections In NewbornsNeonatal Antifungal TherapyNeonatal Fungal InfectionOpportunistic Fungal InfectionsPathogenesis Of Opportunistic PathogensPediatric Fungal Infection
We report the first two documented cases of neonatal zygomycosis caused by Absidia corymbifera. A premature infant developed disseminated disease from a cutaneous site with pulmonary, gastrointestinal, and cerebral involvement. The infant died despite amphotericin B therapy and surgical debridement. The second case occurred in a full-term infant with congenital heart disease and fungal pneumonitis. Zygomycosis was not suspected because of underlying cardiac disease and a complicated postoperative course, and this infant also died. Absidia joins a growing list of opportunistic fungal pathogens of the compromised neonate.
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Antimicrobial defenses in the neonate.
PubMed · 1990 · 62 citations
Medicine, Endocrinology, Obstetrics +12