Infection and Immunity · 2000 · 60 citations · 11 references
Life SciencesMicrobiologyMolecular BiologyBacteriologyHost-pathogen InteractionsMicrobial PathogenesisBacterial PathogenesisBacterial Virulence FactorsMicrobial Virulence FactorsPathogen AdhesionPathogen GenomicsPathogen Virulence FactorsChronic Pseudomonas Aeruginosa InfectionFunctional Genomics Of PathogenicityIron Acquisition SystemsMicrobial Iron AcquisitionPathogenicity Factor ExpressionSequence IdentityVirulence Factor ExpressionVirulence Gene Expression
In vivo expression technology was used for testing Pseudomonas aeruginosa in the rat lung model of chronic infection and in a mouse model of systemic infection. Three of the eight ivi proteins found showed sequence identity to known virulence factors involved in iron acquisition via an open reading frame (called pvdI) implicated in pyoverdine biosynthesis, membrane biogenesis (FtsY), and adhesion (Hag2).
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Pyoverdin is essential for virulence of Pseudomonas aeruginosa
Jean‐Marie Meyer, Alice N. Neely, Alain Stintzi et al. · Infection and Immunity · 1996 · 525 citations · Full text
A rat model of chronic respiratory infection with Pseudomonas aeruginosa.
Howard A. Cash, Donald E. Woods, B. D. McCullough et al. · PubMed · 1979 · 334 citations