The <scp>TLR</scp>2 Ligand <scp>FSL</scp>‐1 and the <scp>TLR</scp>5 Ligand Flagellin Mediate Pro‐Inflammatory and Pro‐Labour Response via MyD88/<scp>TRAF</scp>6/<scp>NF</scp>‐κB‐Dependent Signalling

Abstract

TLR2 engagement by the synthetic lipoprotein FSL-1 and TLR5 engagement by bacterial flagellin enhances pro-inflammatory and pro-labour mediators in human fetal membranes and myometrium via MyD88/TRAF6/NF-κB.