Clinical Experience of Serious Infections Caused by Enterobacteriaceae Producing VIM-1 Metallo- -Lactamase in a Greek University Hospital

Abstract

MBL-producing Enterobacteriaceae can cause severe, often fatal infection in severely ill patients, irrespective of the MIC of carbapenems. Colonization with an MBL-producer is a preceding event, highlighting the importance of surveillance. Both infection control practices and antibiotic policies should be intensified to contain the spread of these problematic bacteria.