Concepedia

SOX4 expression is associated with treatment failure and chemoradioresistance in oral squamous cell carcinoma

Tae Mi Yoon, Sun‐Ae Kim, Wan Seok Cho, Dong Hoon Lee, Joon Kyoo Lee, Young‐Lan Park, Kyung‐Hwa Lee, Jae Hyuk Lee, Sun‐Seog Kweon, Ik‐Joo Chung,

BMC Cancer · 2015 · 34 citations · 20 references

DOIFull text

Open access

Abstract

SOX4 may contribute to oncogenic phenotypes of HNSCC cells by promoting cell survival and causing chemoradioresistance. It could be a potential prognostic marker for OSCC.

References

20

Cancer statistics, 2013

Rebecca L. Siegel, Deepa Naishadham, Ahmedin Jemal · CA A Cancer Journal for Clinicians · 2013 · 11.9K citations · Full text

Defects in cardiac outflow tract formation and pro-B-lymphocyte expansion in mice lacking Sox-4

Marco W. Schilham, Mariëtte A. Oosterwegel, Petra Moerer et al. · Nature · 1996 · 481 citations

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Sex-Determining Region Y Box 4 Is a Transforming Oncogene in Human Prostate Cancer Cells

Pengbo Liu, Sumathi Ramachandran, Mohamed Ali‐Seyed et al. · Cancer Research · 2006 · 298 citations

SOX4 Induces Epithelial–Mesenchymal Transition and Contributes to Breast Cancer Progression

Jianchao Zhang, Qian Liang, Lei Yang et al. · Cancer Research · 2012 · 281 citations · Full text

, , +14

Epigenetic Repression of <i>microRNA-129-2</i> Leads to Overexpression of <i>SOX4</i> Oncogene in Endometrial Cancer

Yi-Wen Huang, Joseph C. Liu, Daniel E. Deatherage et al. · Cancer Research · 2009 · 266 citations · Full text