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The Role of Rac1 in Glycoprotein Ib-IX–Mediated Signal Transduction and Integrin Activation

DOIFull Paper Access

45

Citations

41

References

2012

Year

Michael Keegan Delaney, Junling Liu, Yi Zheng, Michael C. Berndt, Xiaoping Du
Arteriosclerosis Thrombosis and Vascular Biology

Abstract

A Lyn-Vav-Rac1-PI3K-Akt pathway mediates von Willebrand factor-induced activation of integrin α(IIb)β(3) to promote GPIb-IX-dependent platelet activation.

References

YearCitations

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