A Simple and Specific Assay for Real‐Time Colorimetric Visualization of β‐Lactamase Activity by Using Gold Nanoparticles

Abstract

The color of gold: Bacterial β-lactamases (Blas) can be rapidly identified by a simple and specific colorimetric assay with gold nanoparticles (Au-NPs). This assay can evaluate enzymatic kinetic reactions and screen inhibitors of Blas in real time, and offers a simple and economical method for the rapid detection of β-lactam resistant bacteria in clinical studies. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2002/2007/z702773_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.