A Simple and Specific Assay for Real‐Time Colorimetric Visualization of β‐Lactamase Activity by Using Gold Nanoparticles

Abstract

The color of gold: Bacterial β-lactamases (Blas) can be rapidly identified by a simple and specific colorimetric assay with gold nanoparticles (Au-NPs). This assay can evaluate enzymatic kinetic reactions and screen inhibitors of Blas in real time, and offers a simple and economical method for the rapid detection of β-lactam resistant bacteria in clinical studies.