A Novel Approach for the Synthesis of Furopyrimidine and Oxobenzofuran Derivatives

Abstract

Abstract A novel, efficient one‐pot approach for the synthesis of furopyrimidine and oxobenzofuran derivatives 4 by a multicomponent reaction of an isocyanide, an aldehyde, and a CH‐acid compound in CH 2 Cl 2 is reported ( Scheme 1 and Table ). The reactions were completed after 20 h at room temperature. This method has the advantages of high yields, simple methodology, and easy workup.