A New Generation of Air Stable, Highly Active Pd Complexes for CC and CN Coupling Reactions with Aryl Chlorides

Abstract

High yields in important Pd-catalyzed reactions of aryl chlorides (see scheme) are obtained with complexes consisting of a palladacycle and a secondary phosphane which could be prepared in situ or isolated. The latter were shown to be stable, and easy to handle in air, and the in situ catalysts allow optimization of the catalyst by variation of the two components.