Pharmacokinetics of chlorpromazine and key metabolites

In vitro inhibition studies of two isozymes of human liver cytochrome P-450. Mephenytoin p-hydroxylase and sparteine monooxygenase.

T. Inaba, M Jurima, W. A. Mahon et al. · Drug Metabolism and Disposition · 1985 · 180 citations

Medicine, Medicinal Chemistry, Pharmacology +16

Disposition of perphenazine is related to polymorphic debrisoquin hydroxylation in luman beings

Marja‐Liisa Dahl‐Puustinen, Anders Lidén, Christina Alm et al. · Clinical Pharmacology & Therapeutics · 1989 · 165 citations

Medicine, Pharmacokinetics, Pharmacology +12

Plasma levels of thioridazine and metabolites are influenced by the debrisoquin hydroxylation phenotype

Christer von Bahr, G. Movin, Conny Nordin et al. · Clinical Pharmacology & Therapeutics · 1991 · 159 citations

Pharmacy, Pharmacokinetics, Pharmacology +6

Xenobiotic and endobiotic inhibitors of cytochrome p-450dbl function, the target of the debrisoouine/sparteine type polymorphism

Raymonde Fonné‐Pfister, Urs Meyer · Biochemical Pharmacology · 1988 · 117 citations

Medicine, Molecular Biology, Pharmacology +13

Pharmacokinetics of chlorpromazine after single and chronic dosage

Svein G. Dahl, R. E. Strandjord · Clinical Pharmacology & Therapeutics · 1977 · 105 citations

Pharmacy, Pharmacokinetics, Pharmacology +8