Archives of Disease in Childhood · 1975 · 30 citations · 14 references
MedicinePediatricsRespiratory TherapyCardiothoracic SurgeryPulmonologyVentilator ManagementContinuous Positive Airway PressureMechanical VentilationPediatric Respiratory CarePositive Airway Pressure TherapyPulmonary MechanicsRespiratory Distress In NewbornsAirway Management In InfantsCongenital Heart Disease PathophysiologyCongenital Valvular Heart DiseaseLung Tissue MechanicsMinute Ventilation ResponseNeonatal Mechanical VentilationNeonatal Respiratory PhysiologyPediatric Positive Airway Pressure Therapy
The effect of continuous positive airway pressure (CPAP) on lung mechanics was investigated in 12 babies after operation for severe congenital heart disease. At the time of study all babies were receiving or being weaned from ventilatory support and had abnormally low lung volume or compliance. During CPAP there was a fall in the pulmonary resistance which, with a slight decrease in minute ventilation, resulted in a significant decrease in the work of breathing. It is suggested that lowering the oxygen cost of breathing may contribute to the improvement in arterial oxygenation seen when CPAP is used.
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Arthur B. DuBois, Stella Y. Botelho, George N. Bedell et al. · Journal of Clinical Investigation · 1956 · 1.3K citations · Full text
Elasticity of human lungs in relation to age
James M. Turner, J. Mead, Mary Ellen B. Wohl · Journal of Applied Physiology · 1968 · 529 citations