Simpson's Paradox and the Impact of Different <i>DNMT3A</i> Mutations on Outcome in Younger Adults With Acute Myeloid Leukemia

Abstract

These data confirm that presence of a DNMT3A mutation should be considered as a poor-risk prognostic factor, irrespective of the NPM1 genotype, and suggest that further consideration should be given to the type of DNMT3A mutation.