A MLH1 polymorphism that increases cancer risk is associated with better outcome in sporadic colorectal cancer

Analysis of any point mutation in DNA. The amplification refractory mutation system (ARMS)

Charles R. Newton, Alexander Graham, Lesley Heptinstall et al. · Nucleic Acids Research · 1989 · 2.5K citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Mutation in the DNA mismatch repair gene homologue hMLH 1 is associated with hereditary non-polyposis colon cancer

Christian Bronner, Sean M. Baker, Paul T. Morrison et al. · Nature · 1994 · 2.1K citations

Life Sciences, Genetics, Molecular Genetics +12

Incidence and functional consequences of <i>hMLH1</i> promoter hypermethylation in colorectal carcinoma

James G. Herman, Asad Umar, Kornélia Polyák et al. · Proceedings of the National Academy of Sciences · 1998 · 1.9K citations · Full text

Medicine, Genetics, Oncology +17

Mutation of a <i>mutL</i> Homolog in Hereditary Colon Cancer

Nickolas Papadopoulos, Nicholas C. Nicolaides, Ying-Fei Wei et al. · Science · 1994 · 1.8K citations

Life Sciences, Genetics, Molecular Genetics +17

Hypermethylation of the hMLH1 promoter in colon cancer with microsatellite instability.

Julie M. Cunningham, Eric R. Christensen, David J. Tester et al. · PubMed · 1998 · 875 citations

Life Sciences, Genetics, Oncology +17