Medical Decision Making · 2012 · 145 citations · 49 references
Veterinary MedicineInfectious DiseasesBiological Systems ModelingHost-pathogen InteractionsInfectious Disease EpidemiologyDisease ModelingDisease SpreadInfectious Disease DynamicsPathogen TransmissionTransmission DynamicsDisease Transmission InteractionsEpidemic ModelsInfectious Disease ModelsMathematical Modeling Of EpidemicsTime-varying Force Of InfectionTransmission Dynamics Modeling
The transmissible nature of communicable diseases is what sets them apart from other diseases modeled by health economists. The probability of a susceptible individual becoming infected at any one point in time (the force of infection) is related to the number of infectious individuals in the population, will change over time, and will feed back into the future force of infection. These nonlinear interactions produce transmission dynamics that require specific consideration when modeling an intervention that has an impact on the transmission of a pathogen. Best practices for designing and building these models are set out in this paper.
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