Medical Decision Making · 2012 · 138 citations · 49 references
EngineeringViral DynamicEpidemiological DynamicCommunicable DiseasesTransmission SystemComputational EpidemiologyChannel ModelingInfectious Disease ModellingSystems EngineeringDynamic Transmission ModelingTransmission DynamicsDisease ModelsEpidemiologyVaccinationInfectious Disease ModelingTransmissible NatureDisease TransmissionChannel ModelMedicine
The transmissible nature of communicable diseases is what sets them apart from other diseases modeled by health economists. The probability of a susceptible individual becoming infected at any one point in time (the force of infection) is related to the number of infectious individuals in the population, will change over time, and will feed back into the future force of infection. These nonlinear interactions produce transmission dynamics that require specific consideration when modeling an intervention that has an impact on the transmission of a pathogen. Best practices for designing and building these models are set out in this paper.
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