Concepedia

Thiopurine withdrawal during sustained clinical remission in inflammatory bowel disease: relapse and recapture rates, with predictive factors in 237 patients

Nicholas A. Kennedy, Rahul Kalla, Ben Warner, C. J. Gambles, R. Musy, Spencer Reynolds, Rakesh Dattani, H. Nayee, Richard Felwick, Richard Harris,

Alimentary Pharmacology & Therapeutics · 2014 · 64 citations · 24 references

DOIFull text

Open access

Abstract

Thiopurine withdrawal in the context of sustained remission is associated with a 1-year moderate-to-severe relapse rate of 23% in Crohn's disease and 12% in ulcerative colitis.

References

24

Lymphoproliferative disorders in patients receiving thiopurines for inflammatory bowel disease: a prospective observational cohort study

Laurent Beaugerie, Nicole Brousse, Anne‐Marie Bouvier et al. · The Lancet · 2009 · 1.1K citations

, , +4

Treatment of Crohn's Disease with 6-Mercaptopurine

Daniel H. Present, Burton I. Korelitz, Nathaniel Wisch et al. · New England Journal of Medicine · 1980 · 1K citations

, , +7

Fecal calprotectin is a surrogate marker for endoscopic lesions in inflammatory bowel disease

Geert D’Haens, Marc Ferrante, Séverine Vermeire et al. · Inflammatory Bowel Diseases · 2012 · 797 citations · Full text

A multicenter trial of 6-mercaptopurine and prednisone in children with newly diagnosed Crohn's disease

James Markowitz, Kathy Grancher, Nina Kohn et al. · Gastroenterology · 2000 · 725 citations

, , +4

The efficacy of azathioprine for the treatment of inflammatory bowel disease: a 30 year review

Alan G. Fraser · Gut · 2002 · 626 citations · Full text