Concepedia

Electron Microscopy Reveals that Transcription Factor TFIIIA Bends 5S DNA

David P. Bazett‐Jones, M.L Brown

Molecular and Cellular Biology · 1989 · 37 citations · 19 references

DOI

Concepts

Abstract

We have used a high-resolution analytical electron microscopic technique, electron spectroscopic imaging, to study the in vitro interaction between the transcription factor IIIA (TFIIIA) and 5S ribosomal gene DNA. The images and analytical measurements support our proposal that the helix axis is bent by the protein into a hairpin-shaped configuration.

References

19

Repetitive zinc‐binding domains in the protein transcription factor IIIA from Xenopus oocytes.

Jim Miller, A. McLachlan, A. Klug · The EMBO Journal · 1985 · 2.5K citations · Full text

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Specific interaction of a purified transcription factor with an internal control region of 5S RNA genes

David R. Engelke, Siok‐Bian Ng, B.S. Shastry et al. · Cell · 1980 · 776 citations

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A control region in the center of the 5S RNA gene directs specific initiation of transcription: II. The 3′ border of the region

Daniel Bogenhagen, Shigeru Sakonju, Donald D. Brown · Cell · 1980 · 735 citations

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A control region in the center of the 5S RNA gene directs specific initiation of transcription: I. The 5′ border of the region

Shigeru Sakonju, Daniel Bogenhagen, Donald D. Brown · Cell · 1980 · 579 citations

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A specific transcription factor that can bind either the 5S RNA gene or 5S RNA.

Hugh R.B. Pelham, Donald D. Brown · Proceedings of the National Academy of Sciences · 1980 · 513 citations · Full text

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