Pak Functions Downstream of Dock to Regulate Photoreceptor Axon Guidance in Drosophila

A brain serine/threonine protein kinase activated by Cdc42 and Rac1

Edward Manser, Thomas Leung, Harfizah Salihuddin et al. · Nature · 1994 · 1.5K citations

Signal Transduction, Molecular Neuroscience, Molecular Physiology +8

Distinct morphogenetic functions of similar small GTPases: Drosophila Drac1 is involved in axonal outgrowth and myoblast fusion.

Liqun Luo, Yanhong Liao, Lily Yeh Jan et al. · Genes & Development · 1994 · 995 citations · Full text

Genetics, Molecular Genetics, Cytoskeleton +19

PAK Kinases Are Directly Coupled to the PIX Family of Nucleotide Exchange Factors

Edward Manser, Tsui-Han Loo, Cheng-Gee Koh et al. · Molecular Cell · 1998 · 747 citations · Full text

Signal Transduction, Molecular Physiology, Signaling Pathway +12

Human p21-activated kinase (Pak1) regulates actin organization in mammalian cells

Mary Ann Sells, Ulla G. Knaus, Shubha Bagrodia et al. · Current Biology · 1997 · 690 citations · Full text

A Conserved Binding Motif Defines Numerous Candidate Target Proteins for Both Cdc42 and Rac GTPases

Peter D. Burbelo, David Drechsel, Alan Hall · Journal of Biological Chemistry · 1995 · 622 citations · Full text