Concepedia

A covalently linked phenanthridine–ruthenium(ii) complex as a RNA probe

Naphtali O’Connor, Nathan Stevens, Diana Samaroo, Marissa R. Solomon, Ángel A. Martí, Joanne Dyer, Harshad D. Vishwasrao, Daniel L. Akins, Eric R. Kandel, Nicholas J. Turro

Chemical Communications · 2009 · 89 citations · 10 references

DOIFull text

Open access

Concepts

Abstract

A phenanthridine derivative covalently linked to a ruthenium complex yields an imaging probe whose fluorescence intensity and lifetime change substantially in the presence of RNA.

References

10

Photophysics of ruthenium complexes bound to double helical DNA

Challa V. Kumar, Jacqueline K. Barton, Nicholas J. Turro · Journal of the American Chemical Society · 1985 · 612 citations

, , +17

Mechanism of ethidium bromide fluorescence enhancement on binding to nucleic acids

J. Olmsted, David R. Kearns · Biochemistry · 1977 · 557 citations

Lanthanide Luminescent Bioprobes (LLBs)

Jean‐Claude G. Bünzli · Chemistry Letters · 2008 · 183 citations · Full text

, , +16

Two Color RNA Intercalating Probe for Cell Imaging Applications

Nathan Stevens, Naphtali O’Connor, Harshad D. Vishwasrao et al. · Journal of the American Chemical Society · 2008 · 166 citations · Full text

The DNA and RNA specificity of eilatin Ru(II) complexes as compared to eilatin and ethidium bromide

Nathan W. Luedtke · Nucleic Acids Research · 2003 · 86 citations · Full text