Concepedia

Treatment Outcomes for T4 Oropharyngeal Squamous Cell Carcinoma

Joseph Zenga, Michael L. Wilson, Douglas R. Adkins, Hiram A. Gay, Bruce H. Haughey, Dorina Kallogjeri, Loren S. Michel, Randal C. Paniello, Jason T. Rich, Wade L. Thorstad,

JAMA Otolaryngology–Head & Neck Surgery · 2015 · 44 citations · 53 references

DOIFull text

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Abstract

Primary surgical treatment may be associated with improved outcomes in patients with T4 OPSCC. p16 Immunohistochemical status remains a strong prognostic indicator even in patients with locally advanced disease.

References

53

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Human Papillomavirus and Survival of Patients with Oropharyngeal Cancer

K. Kian Ang, Jonathan Harris, Richard Wheeler et al. · New England Journal of Medicine · 2010 · 6.4K citations · Full text

Defining risk levels in locally advanced head and neck cancers: A comparative analysis of concurrent postoperative radiation plus chemotherapy trials of the EORTC (#22931) and RTOG (# 9501)

Jacques Bernier, Jay S. Cooper, Thomas F. Pajak et al. · Head & Neck · 2005 · 1.7K citations

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Final Results of the 94–01 French Head and Neck Oncology and Radiotherapy Group Randomized Trial Comparing Radiotherapy Alone With Concomitant Radiochemotherapy in Advanced-Stage Oropharynx Carcinoma

Fabrice Denis, P. Garaud, É. Bardet et al. · Journal of Clinical Oncology · 2003 · 888 citations

Induction chemotherapy followed by concurrent chemoradiotherapy (sequential chemoradiotherapy) versus concurrent chemoradiotherapy alone in locally advanced head and neck cancer (PARADIGM): a randomised phase 3 trial

Robert I. Haddad, Anne O’Neill, Guilherme Rabinowits et al. · The Lancet Oncology · 2013 · 735 citations

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