Neurology · 2011 · 92 citations · 19 references
Over 10% of patients with MS experience a malignant course as defined above. Some demographic and clinical factors are found to predict a malignant outcome. MS in patients who reach a high EDSS based on disease progression is more likely to remain malignant.
19
Defining the clinical course of multiple sclerosis
Fred Lublin, Stephen C. Reingold · Neurology · 1996 · 3.7K citations
Neurological Disorder, Patient Selection, Clinical Neurology +17
THE NATURAL HISTORY OF MULTIPLE SCLEROSIS: A GEOGRAPHICALLY BASED STUDY
Brian G. Weinshenker, B. Bass, George P. Rice et al. · Brain · 1989 · 1.5K citations
Relapses and Progression of Disability in Multiple Sclerosis
Christian Confavreux, Sandra Vukusic, Thibault Moreau et al. · New England Journal of Medicine · 2000 · 1.3K citations · Full text
Multiple Sclerosis Severity Score
Richard Roxburgh, Shaun R. Seaman, Thomas Masterman et al. · Neurology · 2005 · 945 citations