Concepedia

Functional Characterization of a Putative Serine Carboxypeptidase in Vascular Smooth Muscle Cells

Ting-Hein Lee, Jiyuan Chen, Joseph M. Miano

Circulation Research · 2009 · 18 citations · 18 references

DOIFull text

Open access

Abstract

SCPEP1 promotes smooth muscle cell proliferation and migration in a catalytic triad-dependent, cleavage-independent manner. SCPEP1 represents a new mediator of vascular remodeling and a potential therapeutic target for the treatment of vascular occlusive diseases.

References

18

Kinetics of cellular proliferation after arterial injury. I. Smooth muscle growth in the absence of endothelium.

Clowes Aw, Reidy Ma, Clowes Mm · PubMed · 1983 · 1.4K citations

Activation mechanisms of matrix metalloproteinases.

Hideaki Nagase · PubMed · 1997 · 1.1K citations

, , +18

Remodeling With Neointima Formation in the Mouse Carotid Artery After Cessation of Blood Flow

Anjali Kumar, Volkhard Lindner · Arteriosclerosis Thrombosis and Vascular Biology · 1997 · 524 citations · Full text

PDGF ligand and receptor gene expression during repair of arterial injury.

Mark W. Majesky, M A Reidy, Daniel F. Bowen‐Pope et al. · The Journal of Cell Biology · 1990 · 434 citations · Full text

, , +22

Smooth muscle myosin heavy chain exclusively marks the smooth muscle lineage during mouse embryogenesis.

Joseph M. Miano, Peter Cserjesi, Keith L. Ligon et al. · Circulation Research · 1994 · 412 citations

, , +22