A Domino Copper‐Catalyzed CN and CO Cross‐Coupling for the Conversion of Primary Amides into Benzoxazoles

Abstract

Abstract Benzoxazoles can be efficiently prepared in a single step and in good yield from primary amides and o ‐dihalobenzenes using Cu catalysis. Starting from substituted o ‐bromochlorobenzenes this unusual domino reaction allows the regioselective formation of benzoxazoles.