Mechanism of Mitotic Block and Inhibition of Cell Proliferation by the Semisynthetic<i>Vinca</i>Alkaloids Vinorelbine and Its Newer Derivative Vinflunine

Dynamic instability of microtubule growth

Tim Mitchison, Marc W. Kirschner · Nature · 1984 · 3.3K citations

Pattern Formation, Cell Division, Morphogenesis +7

Mechanism of mitotic block and inhibition of cell proliferation by taxol at low concentrations.

Mary Ann Jordan, Robert Toso, Douglas Thrower et al. · Proceedings of the National Academy of Sciences · 1993 · 1.1K citations · Full text

Nm Taxol, Cell Death, Cell Culture +17

Mitotic block induced in HeLa cells by low concentrations of paclitaxel (Taxol) results in abnormal mitotic exit and apoptotic cell death.

M A Jordan, K Wendell, Sheila M. Gardiner et al. · PubMed · 1996 · 783 citations

Apoptosis, Cell Death, Cell Proliferation +20

Polewards microtubule flux in the mitotic spindle: evidence from photoactivation of fluorescence.

Timothy J. Mitchison · The Journal of Cell Biology · 1989 · 611 citations · Full text

Cell Division, Microscopy, Natural Sciences +14

Mechanism of inhibition of cell proliferation by Vinca alkaloids.

M A Jordan, Douglas Thrower, L Wilson · PubMed · 1991 · 539 citations

Chromatin, Spindle Organization, Vinca Alkaloids +14