Increased and Expedited Case Detection by Xpert MTB/RIF Assay in Childhood Tuberculosis: A Prospective Cohort Study

Andrea Rachow, Petra Clowes, Elmar Saathoff, Bariki Mtafya, Epiphania Michael, Elias N. Ntinginya, Dickens Kowour, Gabriel Rojas-Ponce, Arne Kroidl, Leonard Maboko,

Clinical Infectious Diseases · 2012 · 142 citations · 21 references

DOIFull text

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Abstract

Xpert was easy to perform and displayed similar diagnostic accuracy as culture methods in children with suspected tuberculosis. Rapid turnaround times should reduce treatment delay and improve patient outcome, although sensitivity remains suboptimal and access is dependent on local laboratory infrastructure.

References

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