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Effects of Tranexamic Acid on Blood Loss during Total Hip Arthroplasty

Jagwant Singh, Moez S. Ballal, Philip B. Mitchell, P. G Denn

Journal of orthopaedic surgery · 2010 · 51 citations · 24 references

DOIFull text

Open access

Abstract

A single dose of intravenous TA (10 mg per kg body weight) given 10 minutes prior to THA is a cost-effective and safe means of minimising blood loss and reduction in haemoglobin concentrations as well as the need for allogenic blood transfusion, without increasing the risk of thromboembolic events.

References

24

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Andreas Laupacis, Dean Fergusson · Anesthesia & Analgesia · 1997 · 300 citations

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Tranexamic acid in total hip arthroplasty saves blood and money

Torsten Johansson, Lars-Göran Pettersson, B. Lisander · Acta Orthopaedica · 2005 · 203 citations · Full text

Blood conservation with tranexamic acid in total hip arthroplasty: A randomized, double-blind study in 40 primary operations

Göran Benoni, Hans Fredin, Richard Knebel et al. · Acta Orthopaedica Scandinavica · 2001 · 183 citations

Tranexamic Acid Reduces Blood Loss in Total Hip Replacement Surgery

Gustav Ekbäck, Kjell Axelsson, Lars Ryttberg et al. · Anesthesia & Analgesia · 2000 · 180 citations

, , +18