Prognostic Assessment of Three Single-Nucleotide Polymorphisms (<i>GNB3</i>825C&gt;T,<i>BCL2</i>-938C&gt;A,<i>MCL1</i>-386C&gt;G) in Extrahepatic Cholangiocarcinoma

Abstract

GNB3 825C>T SNP may be a novel independent prognostic marker for patients suffering from extrahepatic CCA with the CC genotype to be associated with a favorable clinical outcome. Further prospective studies are needed to confirm these results and reveal additional functional SNP effects.