Concepedia

Circulating Irisin in Relation to Insulin Resistance and the Metabolic Syndrome

Kyung‐Hee Park, Lesya Zaichenko, Mary Brinkoetter, Bindiya Thakkar, Ayse Sahin-Efe, Kyoung Eun Joung, Michael A. Tsoukas, Eleni Geladari, Joo Young Huh, Fadime Dincer,

The Journal of Clinical Endocrinology & Metabolism · 2013 · 505 citations · 31 references

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Abstract

Irisin is associated with increased risk of MetS, cardiometabolic variables, and CVD in humans, indicating either increased secretion by adipose/muscle tissue and/or a compensatory increase of irisin to overcome an underlying irisin resistance in these subjects.

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