Concepedia

Clinical and microbiological impact of discontinuation of fluoroquinolone prophylaxis in patients with prolonged profound neutropenia

Anke Verlinden, Hilde Jansens, Herman Goossens, Ann L. Van de Velde, Wilfried Schroyens, Zwi Berneman, Alain Gadisseur

European Journal Of Haematology · 2014 · 34 citations · 20 references

DOI

Abstract

No clinically relevant short-term drawbacks were observed with the discontinuation of fluoroquinolone prophylaxis in patients with chemotherapy-induced prolonged profound neutropenia, which led to a significant decrease in fluoroquinolone resistance as well as occurrence of ESBL-producing isolates.

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