Concepedia

Effects of discontinuing or continuing ongoing statin therapy in severe sepsis and septic shock: a retrospective cohort study

Armand Mekontso Dessap, Islem Ouanes, Nerlep Rana, Beatrice Borghi, Christophe Bazin, Sandrine Katsahian, Anne Hulin, Christian Brun‐Buisson

Critical Care · 2011 · 26 citations · 16 references

DOI Full text

Open access

Abstract

Continuing statin therapy in ICU septic patients was not associated with reduction in the severity of organ failure after matching and adjustment. In addition, the very high plasma concentrations achieved during continuation of statin treatment advocates some caution.

References

16

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Viral Sepsis, Acute Care, Sepsis +4

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Peter C. Austin · Statistics in Medicine · 2009 · 6.1K citations · Full text

Propensity Score, Health Policy, Matching Technique +14

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Jean‐Louis Vincent, Arnaldo de Mendonça, F. Cantraine et al. · Critical Care Medicine · 1998 · 3.4K citations

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R. Phillip Dellinger, Jean Carlet, Henry Masur et al. · Intensive Care Medicine · 2004 · 3.3K citations · Full text

Trauma Resuscitation, Critical Care Management, Severe Sepsis +9

Gram-Negative Bacteremia

William R. McCabe · Archives of Internal Medicine · 1962 · 1.4K citations

Gram-negative Bacteriology, Pathogenic Microbiology, Antimicrobial Susceptibility +14