Concepedia

Toll-like receptor 3 upregulation in macrophages participates in the initiation and maintenance of pristane-induced arthritis in rats

Liesu Meng, Wenhua Zhu, Congshan Jiang, Xiaojing He, Weikun Hou, Fang Zheng, Rikard Holmdahl, Shemin Lu

Arthritis Research & Therapy · 2010 · 57 citations · 46 references

Open access

Abstract

TLR3 plays a pivotal role in the initiation and development of PIA which may dependent on macrophage. These findings are useful to understand the pathogenesis of RA and may provide an intriguing therapeutic opportunity for RA.

References

46

Toll-Like Receptor Signaling Pathways

Gregory M. Barton, Ruslan Medzhitov · Science · 2003 · 1.2K citations

Adaptive Immune System, Innate Immune System, Immunology +17

Toll-like receptor 2 controls expansion and function of regulatory T cells

Roger P.M. Sutmuller · Journal of Clinical Investigation · 2006 · 746 citations · Full text

T-regulatory Cell, Innate Immune System, Immunology +17

Arthritis Critically Dependent on Innate Immune System Players

Hong Ji, Koichiro Ohmura, Umar Mahmood et al. · Immunity · 2002 · 689 citations · Full text

Inflammation, Rheumatology, Rheumatoid Disorder +8

Stimulation of TLR2 and TLR4 differentially skews the balance of T cells in a mouse model of arthritis

Shahla Abdollahi‐Roodsaz, Leo A. B. Joosten, Marije I. Koenders et al. · Journal of Clinical Investigation · 2008 · 523 citations · Full text

Toll-like receptor 2 signaling modulates the functions of CD4 <sup>+</sup> CD25 <sup>+</sup> regulatory T cells

Haiying Liu, Mousa Komai‐Koma, Damo Xu et al. · Proceedings of the National Academy of Sciences · 2006 · 436 citations · Full text