Catecholamine Metabolites in Urine, as Chronic Stress Biomarkers, Are Associated With Higher Risk of Chronic Periodontitis in Adults

Abstract

The present results offer new evidence of the association between urinary concentrations of catecholamine metabolites (metanephrine and total metanephrines) and chronic periodontitis. Salivary IgA level showed no statistical difference between the cases and controls. Salivary cortisol levels in the patients with periodontitis were correlated with worse PI, higher gingival inflammation, and greater tooth loss.