Concepedia

Suppression of inflammatory responses by celastrol, a quinone methide triterpenoid isolated from<i>Celastrus regelii</i>

D H Kim, Eun-Jung Shin, Y. H. Kim, B. W. Lee, Jong‐Gab Jun, Ji Hyeon Park, J.‐K. Kim

European Journal of Clinical Investigation · 2009 · 111 citations · 20 references

DOI

Abstract

Our data suggest that celastrol inhibits the production of inflammatory mediators and is a potential target for the treatment of various inflammatory diseases.

References

20

The role of nitric oxide in innate immunity

Christian Bogdan, Martin Röllinghoff, Andreas Diefenbach · Immunological Reviews · 2000 · 656 citations

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Celastrol, a Triterpene Extracted from the Chinese “Thunder of God Vine,” Is a Potent Proteasome Inhibitor and Suppresses Human Prostate Cancer Growth in Nude Mice

Huanjie Yang, Di Chen, Qiuzhi Cindy Cui et al. · Cancer Research · 2006 · 578 citations

Structure of the human cyclo-oxygenase-2 gene

Susan B. Appleby, Ari Ristimäki, Karen M. Neilson et al. · Biochemical Journal · 1994 · 481 citations · Full text

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Both Erk and p38 Kinases Are Necessary for Cytokine Gene Transcription

Aaron Brent Carter, Martha M. Monick, Gary W. Hunninghake · American Journal of Respiratory Cell and Molecular Biology · 1999 · 304 citations

Serum-regulated transcription by serum response factor (SRF): a novel role for the DNA binding domain.

Caroline S. Hill, Judy Wynne, Richard Treisman · The EMBO Journal · 1994 · 162 citations · Full text

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