Concepedia

Influence of early gut microbiota on the maturation of childhood mucosal and systemic immune responses

Ylva Margareta Sjögren, Sara Tomičić, Anna Lundberg, Malin Fagerås Böttcher, Bengt Björkstén, Eva Sverremark‐Ekström, Maria C. Jenmalm

Clinical & Experimental Allergy · 2009 · 344 citations · 35 references

DOIFull text

Open access

Abstract

Bifidobacterial diversity may enhance the maturation of the mucosal SIgA system and early intense colonization with Bacteroides fragilis might down-regulate LPS responsiveness in infancy.

References

35

An Immunomodulatory Molecule of Symbiotic Bacteria Directs Maturation of the Host Immune System

Sarkis K. Mazmanian, Cui Hua Liu, Arthur O. Tzianabos et al. · Cell · 2005 · 2.8K citations · Full text

, , +10

A microbial symbiosis factor prevents intestinal inflammatory disease

Sarkis K. Mazmanian, June L. Round, Dennis L. Kasper · Nature · 2008 · 2.3K citations

, , +9

Dendritic cells produce IL-12 and direct the development of Th1 cells from naive CD4+ T cells.

S E Macatonia, Nancy Hosken, Mark J. Litton et al. · The Journal of Immunology · 1995 · 1.5K citations

Allergy development and the intestinal microflora during the first year of life

Bengt Björkstén, Epp Sepp, Kaja Julge et al. · Journal of Allergy and Clinical Immunology · 2001 · 1.2K citations · Full text

, , +12

The requirement of intestinal bacterial flora for the development of an IgE production system fully susceptible to oral tolerance induction

Nobuyuki Sudo, S. Sawamura, Kazuo Tanaka et al. · The Journal of Immunology · 1997 · 1.1K citations · Full text