A Systematic Assessment of Radiation Dose Enhancement by 5-Aza-2′-Deoxycytidine and Histone Deacetylase Inhibitors in Head-and-Neck Squamous Cell Carcinoma

Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands.

James G. Herman, Jeremy R. Graff, Sanna Myöhänen et al. · Proceedings of the National Academy of Sciences · 1996 · 5.7K citations

Life Sciences, Genetics, Molecular Biology +17

A gene hypermethylation profile of human cancer.

Manel Esteller, Paul G. Corn, Stephen B. Baylin et al. · PubMed · 2001 · 2K citations

Medicine, Molecular Biology, Oncology +17

Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer

Elizabeth E. Cameron, Kurtis E. Bachman, Sanna Myöhänen et al. · Nature Genetics · 1999 · 1.9K citations

Life Sciences, Molecular Biology, Oncology +12

Phase 1 study of low-dose prolonged exposure schedules of the hypomethylating agent 5-aza-2′-deoxycytidine (decitabine) in hematopoietic malignancies

Jean‐Pierre J. Issa, Guillermo Garcia‐Manero, Francis J. Giles et al. · Blood · 2003 · 817 citations

Medicine, Oncology, Pharmacology +14

Combined DNA Methyltransferase and Histone Deacetylase Inhibition in the Treatment of Myeloid Neoplasms

Steven D. Gore, Stephen B. Baylin, Elizabeth A. Sugar et al. · Cancer Research · 2006 · 472 citations · Full text

Medicine, Oncology, Pharmacotherapy +17