Molecular and Clinical Evidence for an<i>ARMC5</i>Tumor Syndrome: Concurrent Inactivating Germline and Somatic Mutations Are Associated With Both Primary Macronodular Adrenal Hyperplasia and Meningioma - Concepedia

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Molecular and Clinical Evidence for an<i>ARMC5</i>Tumor Syndrome: Concurrent Inactivating Germline and Somatic Mutations Are Associated With Both Primary Macronodular Adrenal Hyperplasia and Meningioma

DOI Full Paper Access

104

Citations

47

References

2014

Year

Ulf Elbelt, Alessia Trovato, Michael Kloth, Enno Gentz, R. Finke, Joachim Spranger, David J. Galas, Susanne N. Weber, Cristina Wolf, Katharina König,

The Journal of Clinical Endocrinology & Metabolism

Abstract

Our analysis further confirms inherited inactivating ARMC5 mutations as a cause of familial PMAH and suggests an additional role for the development of concomitant intracranial meningiomas.

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