Recent synthetic developments in a powerful imino Diels–Alder reaction (Povarov reaction): application to the synthesis of N-polyheterocycles and related alkaloids

Vladímir V. Kouznetsov

Tetrahedron

Related AlkaloidsOrganic ChemistryPovarov ReactionSynthetic ChemistryChemistry +3

Structure−Activity Relationships for a Series of Quinoline-Based Compounds Active against Replicating and Nonreplicating<i>Mycobacterium tuberculosis</i>

Annamaria Lilienkampf, Jialin Mao, Baojie Wan, +3

Journal of Medicinal Chemistry

Novel Tacrine−8-Hydroxyquinoline Hybrids as Multifunctional Agents for the Treatment of Alzheimer’s Disease, with Neuroprotective, Cholinergic, Antioxidant, and Copper-Complexing Properties

María Isabel Fernández‐Bachiller, Concepción Pérez, Gema C. González-Muñoz, +5

Journal of Medicinal Chemistry

New quinoline derivatives: Synthesis and investigation of antibacterial and antituberculosis properties

Sumesh Eswaran, Airody Vasudeva Adhikari, Imran H. Chowdhury, +2

European Journal of Medicinal Chemistry

Derivative (Chemistry)MedicineOrganic ChemistryAntibacterial AgentAntimicrobial Chemotherapy +6

Synthesis and biological evaluation of substituted quinolines: potential treatment of protozoal and retroviral co-infections

M. Fakhfakh, Alain Fournet, Eric Prina, +4

Bioorganic & Medicinal Chemistry

Retroviral Co-infectionsMedicineAntiviral TherapyVirologyMicrobiology +4

Synthesis and in vitro antitubercular activity of a series of quinoline derivatives

M.V.N. De Souza, Karla C. Pais, Carlos R. Kaiser, +3

Bioorganic & Medicinal Chemistry

BiochemistryMedicineVitro Antitubercular ActivityQuinoline DerivativesHeterocycle Chemistry +4

Novel Transient Receptor Potential Vanilloid 1 Receptor Antagonists for the Treatment of Pain:  Structure−Activity Relationships for Ureas with Quinoline, Isoquinoline, Quinazoline, Phthalazine, Quinoxaline, and Cinnoline Moieties

Arthur Gomtsyan, Erol K. Bayburt, Robert G. Schmidt, +20

Journal of Medicinal Chemistry

Pain MedicineImmunologyReceptor AntagonistsNeuropathic PainMolecular Pain +16

2-substituted quinoline alkaloids as potential antileishmanial drugs

Alain Fournet, Angel Barrios, Verónica Francisca Loewe Muñoz, +3

Antimicrobial Agents and Chemotherapy

Medicinal ChemistryLeishmania SppBioorganic ChemistryPharmaceutical ChemistryBiochemistry +12

Studies on Disease-Modifying Antirheumatic Drugs:  Synthesis of Novel Quinoline and Quinazoline Derivatives and Their Anti-inflammatory Effect

Atsuo Baba, Noriaki Kawamura, Haruhiko Makino, +3

Journal of Medicinal Chemistry

Novel QuinolineAa Rat ModelAntiparasitic AgentImmunologyPharmacotherapy +15

Synthesis and evaluation of quinoline carboxyguanidines as antidiabetic agents

Dolorès Edmont, Richard Rocher, Christophe Plisson, +1

Bioorganic & Medicinal Chemistry Letters

MedicineQuinoline CarboxyguanidinesPharmacotherapyPharmacologyAntiviral Compound +2