Unattached Kinetochores Catalyze Production of an Anaphase Inhibitor that Requires a Mad2 Template to Prime Cdc20 for BubR1 Binding

Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochores

Claire Ditchfield, Victoria Johnson, Anthony Tighe et al. · The Journal of Cell Biology · 2003 · 1.2K citations · Full text

Genetics, Molecular Biology, Aurora B +16

Checkpoint inhibition of the APC/C in HeLa cells is mediated by a complex of BUBR1, BUB3, CDC20, and MAD2

Valery Sudakin, Gordon K. Chan, Tim J. Yen · The Journal of Cell Biology · 2001 · 903 citations · Full text

Checkpoint Inhibition, Immunology, Cell Death +17

The checkpoint delaying anaphase in response to chromosome monoorientation is mediated by an inhibitory signal produced by unattached kinetochores.

C L Rieder, Richard W. Cole, A Khodjakov et al. · The Journal of Cell Biology · 1995 · 707 citations · Full text

Cytogenetics, Monooriented Chromosome, Cell Death +21

The checkpoint protein MAD2 and the mitotic regulator CDC20 form a ternary complex with the anaphase-promoting complex to control anaphase initiation

Guowei Fang, Hongtao Yu, Marc W. Kirschner · Genes & Development · 1998 · 590 citations · Full text

Mitotic forces control a cell-cycle checkpoint

Xiaotong Li, R. Bruce Nicklas · Nature · 1995 · 533 citations

Cell Regulation, Cell Division, Medicine +7