Concepedia

Influence of charge on FITC-BSA-loaded chondroitin sulfate-chitosan nanoparticles upon cell uptake in human Caco-2 cell monolayers

Ming-Kung Yeh, Chieh-Shen Hu, Chiao‐Hsi Chiang, Po‐Da Hong

International Journal of Nanomedicine · 2012 · 66 citations · 22 references

DOIFull text

Open access

Abstract

The ChS-CS nanoparticles fabricated in this study were effectively endocytosed by Caco-2 fibroblasts without significant cytotoxicity at high nanoparticle concentrations. ChS-CS nanoparticles represent a potential novel delivery system for the transport of hydrophilic macromolecules.

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