Neuronal guidance molecule netrin-1 attenuates inflammatory cell trafficking during acute experimental colitis - Concepedia

Concepedia

Publication | Open Access

Neuronal guidance molecule netrin-1 attenuates inflammatory cell trafficking during acute experimental colitis

DOI Full Paper Access

125

Citations

53

References

2011

Year

Carol M. Aherne, Colm B. Collins, Joanne C. Masterson, Marco Tizzano, Theresa A. Boyle, Joseph A. Westrich, Jason Parnes, Glenn T. Furuta, Jesús Rivera–Nieves, Holger K. Eltzschig

Abstract

The present study identifies a previously unrecognised role for netrin-1 in attenuating experimental colitis through limitation of neutrophil trafficking.

References

	Year	Citations
The netrins define a family of axon outgrowth-promoting proteins homologous to C. elegans UNC-6 Tito Serafini, Timothy E. Kennedy, Michael J. Gaiko, Cell Molecular NeuroscienceDevelopmental BiologyDevelopmental GeneticsAxon Outgrowth-promoting ProteinsMorphogenesis	1994	1.4K
Netrins are diffusible chemotropic factors for commissural axons in the embryonic spinal cord Timothy E. Kennedy, Tito Serafini, José R. de la Torre, Cell Developmental BiologySpinal Cord InjuryNeuroanatomyCommissural AxonsMedicine	1994	1.3K
HMEC-1: Establishment of an Immortalized Human Microvascular Endothelial Cell Line Edwin W. Ades, Francisco J. Candal, Robert A. Swerlick, Journal of Investigative Dermatology AngiogenesisEndothelial DysfunctionVascular BiologyBiomedical EngineeringNeovascularization	1992	1.3K
Lamina propria macrophages and dendritic cells differentially induce regulatory and interleukin 17–producing T cell responses Timothy L. Denning, Yichong Wang, Seema R. Patel, Nature Immunology InflammationCytokineT Cell ResponsesT-regulatory CellInnate Immune System	2007	970
Proinflammatory Cytokines Disrupt Epithelial Barrier Function by Apoptosis-Independent Mechanisms Matthias Bruewer, Andreas Luegering, Torsten Kucharzik, The Journal of Immunology ApoptosisImmunologyImmune RegulationCell DeathMucosal Barrier Function	2003	890
Epithelial hypoxia-inducible factor-1 is protective in murine experimental colitis Jörn Karhausen, Glenn T. Furuta, John E. Tomaszewski, Journal of Clinical Investigation InflammationChronic Inflammatory DiseasesAdaptive Hypoxia ResponsesMucosal ImmunologyImmunology	2004	566
Epithelial hypoxia-inducible factor-1 is protective in murine experimental colitis Jörn Karhausen, Glenn T. Furuta, John E. Tomaszewski, Journal of Clinical Investigation InflammationChronic Inflammatory DiseasesAdaptive Hypoxia ResponsesMucosal ImmunologyImmunology	2004	552
Neutrophil Transmigration in Inflammatory Bowel Disease Is Associated with Differential Expression of Epithelial Intercellular Junction Proteins Torsten Kucharzik, Shaun Walsh, Jason Chen, American Journal Of Pathology InflammationDifferential ExpressionCell TraffickingImmunologyGastroenterology	2001	514
The Hydroxylase Inhibitor Dimethyloxalylglycine Is Protective in a Murine Model of Colitis Eoin P. Cummins, Fergal Seeballuck, Stephen J. Keely, Gastroenterology InflammationMucosal ImmunologyBiochemistryMedicineMurine Model	2007	399
Hypoxia-inducible factor–dependent induction of netrin-1 dampens inflammation caused by hypoxia Peter Rosenberger, Jan M. Schwab, Valbona Mirakaj, Nature Immunology	2009	399

Page 1