Peptidases Play an Important Role in Cataractogenesis: An Immunohistochemical Study on Lenses Derived from Shumiya Cataract Rats

Selenite nuclear cataract: review of the model.

Thomas R. Shearer, Hong Ma, Chiho Fukiage et al. · PubMed · 1997 · 197 citations

Ocular Disease, Selenite Overdose Cataract, Ophthalmology +13

Sequence analysis of lens beta-crystallins suggests involvement of calpain in cataract formation.

L.L. David, Thomas R. Shearer, M. Shih · Journal of Biological Chemistry · 1993 · 114 citations · Full text

Ocular Disease, Ophthalmology, Biochemistry +15

Lens proteasome shows enhanced rates of degradation of hydroxyl radical modified alpha-crystallin

Koko Murakami, Jessica H. Jahngen, Sharon W. Lin et al. · Free Radical Biology and Medicine · 1990 · 76 citations

Biochemistry, Lens Proteasome Shows, Protein Folding +5

Interaction between αB-crystallin and the human 20S proteasomal subunit C8/α7

Wilbert C. Boelens, Yvonne Croes, Wilfried W. de Jong · Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology · 2001 · 66 citations

Protein Chemistry, Proteasomal Subunit C8/α7, Protein Function +9

Differential metabolism and leakage of protein in an inherited cataract and a normal lens cultured with ouabain

Joram Piatigorsky, Henry N. Fukui, Jin H. Kinoshita · Nature · 1978 · 56 citations

Ocular Disease, Normal Lens, Ophthalmology +9